Merle phenotypes in dogs - SILV SINE insertions from Mc to Mh.
It has been recognized that the Merle coat pattern in dogs is not only a visually interesting feature, but it also exerts an important biological role, in terms of hearing and vision impairments.In 2006, the Merle (M) locus was mapped to the SILV gene (aka nyx 22 brush PMEL) with a SINE element in it, and the inserted retroelement was proven causat